Shinsuke Nakamura Selected Research

Edaravone

1/2016	Edaravone is a free radical scavenger that protects against laser-induced choroidal neovascularization in mice and common marmosets.
9/2010	Systemic administration of a free radical scavenger, edaravone, protects against light-induced photoreceptor degeneration in the mouse retina.

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Shinsuke Nakamura Research Topics

Disease

12	Retinal Vein Occlusion 01/2024 - 01/2018
12	Papilledema 01/2023 - 01/2018
11	Choroidal Neovascularization 01/2024 - 09/2014
10	Ischemia 01/2022 - 12/2011
9	Macular Degeneration (Age-Related Maculopathy) 01/2024 - 02/2011
8	Retinal Neovascularization 01/2021 - 01/2010
7	Glioblastoma (Glioblastoma Multiforme) 04/2024 - 11/2019
7	Neoplasms (Cancer) 04/2024 - 01/2013
7	Brain Injuries (Brain Injury) 02/2022 - 11/2018
7	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 02/2011
6	Edema (Dropsy) 01/2024 - 01/2021
6	Ganglion Cysts (Ganglion) 01/2023 - 03/2013
5	Reperfusion Injury 10/2023 - 08/2013
5	Hypoxia (Hypoxemia) 01/2022 - 06/2012
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2024 - 01/2020
4	Macular Edema 01/2022 - 01/2017
4	Retinal Degeneration 10/2021 - 01/2018
4	Hematoma 01/2021 - 01/2019
4	Atrophy 01/2021 - 06/2013
4	Blindness (Hysterical Blindness) 01/2021 - 02/2011
4	Intracranial Hemorrhages (Intracranial Hemorrhage) 11/2020 - 01/2019
3	Hemorrhage 06/2024 - 11/2020
3	Glaucoma 02/2024 - 01/2018
3	Brain Ischemia (Cerebral Ischemia) 01/2023 - 07/2018
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 01/2019
3	Ischemic Stroke 01/2023 - 11/2019
3	Fibrosis (Cirrhosis) 01/2022 - 07/2018
3	Inflammation (Inflammations) 07/2021 - 10/2012
3	Pathologic Neovascularization 01/2021 - 06/2012
3	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 12/2020 - 07/2018
3	Infarction (Infarctions) 01/2020 - 11/2019
2	Myocardial Infarction 10/2023 - 01/2020
2	Myocardial Ischemia (Ischemic Heart Diseases) 10/2023 - 01/2020
2	Neuroblastoma 01/2023 - 01/2023
2	Vascular Diseases (Vascular Disease) 01/2023 - 01/2021
2	Infections 02/2022 - 10/2012
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 02/2022 - 01/2022
2	Hemorrhagic Stroke 01/2021 - 11/2019
2	Brain Edema (Cerebral Edema) 01/2020 - 12/2018
2	Stroke (Strokes) 01/2020 - 11/2019
2	Retinal Perforations 01/2017 - 05/2011
2	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2012 - 02/2011
2	Hyperoxia 05/2011 - 01/2010
1	Cardiotoxicity 11/2023
1	Parkinson Disease (Parkinson's Disease) 01/2023
1	Lymphoma (Lymphomas) 01/2023

Drug/Important Bio-Agent (IBA)

25	Retinaldehyde (Retinal)IBA 01/2024 - 02/2011
15	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 06/2012
10	Oxygen (Dioxygen)IBA 01/2023 - 02/2011
8	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2013
7	ProgranulinsIBA 11/2023 - 01/2019
4	IronIBA 06/2024 - 01/2019
4	Neuroprotective AgentsIBA 01/2022 - 09/2014
4	Free Radical ScavengersIBA 01/2021 - 09/2010
3	Hemoglobins (Hemoglobin)IBA 06/2024 - 11/2018
3	Peptides (Polypeptides)IBA 01/2023 - 05/2011
3	Therapeutic UsesIBA 01/2023 - 11/2020
3	Temozolomide (Temodar)FDA LinkGeneric 11/2022 - 11/2019
3	AntioxidantsIBA 12/2021 - 11/2018
3	Collagenases (Collagenase)FDA Link 01/2021 - 11/2018
2	Hemin (Panhematin)FDA Link 06/2024 - 01/2020
2	RotenoneIBA 01/2024 - 10/2021
2	Timolol (Blocadren)FDA LinkGeneric 01/2023 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 09/2014
2	OccludinIBA 01/2023 - 01/2019
2	Alkylating AgentsIBA 11/2022 - 11/2019
2	nafamostatIBA 02/2022 - 01/2022
2	4- (4- acetylpiperazin- 1- yl)- 2- (1H- imidazol- 1- yl)anilineIBA 01/2021 - 11/2019
2	Chelating AgentsIBA 01/2021 - 11/2020
2	adonixanthinIBA 09/2020 - 11/2018
2	astaxanthine (astaxanthin)IBA 09/2020 - 11/2018
2	Levetiracetam (Keppra)FDA LinkGeneric 01/2020 - 07/2019
2	trans-sodium crocetinate (crocetin)IBA 01/2019 - 03/2013
2	Protein Isoforms (Isoforms)IBA 01/2018 - 01/2017
2	EdaravoneIBA 01/2016 - 09/2010
1	LinagliptinIBA 04/2024
1	Dipeptidyl-Peptidase IV InhibitorsIBA 04/2024
1	ASP4058IBA 01/2024
1	CanagliflozinIBA 03/2023
1	Sodium-Glucose Transporter 2 InhibitorsIBA 03/2023
1	cadherin 5IBA 01/2023
1	Nucleic AcidsIBA 01/2023
1	CationsIBA 01/2023
1	CalciumIBA 01/2023
1	GSK2193874IBA 01/2023
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023
1	arctigeninIBA 01/2023
1	ProstaglandinsIBA 01/2023
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2023
1	Ophthalmic Solutions (Eye Drops)IBA 01/2023
1	GSK2798745IBA 01/2023
1	Hematoxylin (Haematoxylon)IBA 01/2023
1	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 01/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2023

Therapy/Procedure

13	Lasers (Laser) 02/2024 - 09/2014
9	Oral Administration 04/2024 - 01/2019
7	Therapeutics 01/2022 - 09/2014
3	Intravitreal Injections 01/2021 - 01/2017
3	Ligation 10/2013 - 12/2011